The search for antibiotic compounds from the natural environment has been going on for seven decades, ever since penicillin entered the market and antibiotic treatments became routine. The evolutionary pressure put on the Pathogenic microorganisms induced a rapid spreading of naturally occurring resistance genes, leaving only the option of finding new antibiotics to treat the resistant pathogens. Microorganisms have been extensively mined for their biosynthetic abilities to produce biologically active compounds. To date, more than 23 000 microbial natural products have been discovered. The Actinomycetales are ubiquitous bacteria that have been used for antibiotic discovery for more than half a century, and over 10 000 natural products have been identified from the order.

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

The aim of the project was to investigate if Swedish rodents, brown rat (Rattus norvegicus), house mouse (Mus musculus), wood mouse (Apodemus spp) and water vole (Arvicola terrestris) captured in pig herds and in urban areas, constitute a reservoir for pathogenic Leptospira spp. Under Swedish conditions leptospirosis gives rise to reproductive disorders in pigs and symptoms of flu in humans. It has long been established that rodents are chronic carriers of pathogenic leptospires in their kidneys, and can spread the bacteria with urine. The old nomenclature of serovoars is still in use, but a new system of genetic classification has developed and today the genus Leptospira contains 17 species. There are several diagnostic test developed for leptospirosis.

Risk-based sampling program of microorganisms in the water source in northern SwedenAfter several disease outbreaks caused by parasites in the drinking water during the last years, it is more essential than ever to insure that the water supply companies have enough barriers to counteract the presence of microorganisms in the outgoing water. It is also discussed whether climate changes such as increased precipitation can have a connection to the increased cases of parasites in water sources. The water source at Gäddvik is Luleå municipality?s largest and provides drinking water to 64 500 of Luleå?s 74 000 inhabitants. The investigation of microorganisms in the water source, especially in the Lule River has not been as prioritized as the sampling of chemical parameters.

The aim of the study was to investigate if some selected recipes could be hazardous for man; that is if pathogenic bacteria in raw ingredients could survive the cooking process. The study included three known pathogens, Listeria monocytogenes, Salmonella Typhimurium and Campylobacter jejuni. A known number of the bacterium chosen was added to the raw product. The dish was prepared according to the recipe and then a bacteriological investigation concerning the added pathogenic bacterium was performed. The results showed that all recipes tested could be hazardous; that is the added pathogen was still living after the cooking process..

In the country of Jordan, egg production is very important economically, but several bacte-ria are involved in food borne diseases transmitted from eggs or other poultry products. The most important are Salmonella spp., Campylobacter jejuni and Escherichia coli. In Jordan two different housing systems are used for hens in large scale egg production; con-ventional cages and litter floor systems. Eggs from four different farms were analysed and compared to see if a difference could be found regarding the presence of pathogenic bacte-ria on the egg surfaces between these two systems. Total number of aerobic bacteria was analysed, the presence of Salmonella spp., C.

In the country of Jordan, egg production is very important economically, but several bacte-ria are involved in food borne diseases transmitted from eggs or other poultry products. The most important are Salmonella spp., Campylobacter jejuni and Escherichia coli. In Jordan two different housing systems are used for hens in large scale egg production; con-ventional cages and litter floor systems. Eggs from four different farms were analysed and compared to see if a difference could be found regarding the presence of pathogenic bacte-ria on the egg surfaces between these two systems. Total number of aerobic bacteria was analysed, the presence of Salmonella spp., C.

The aim of this study was to in laboratory experiments investigate how addition of urea, ECOX and structural materials can optimize sanitization during composting of sewage sludge. Today we strive for a sustainable society and the importance of closing the nutrient loop increases. It has therefore become even more important to safely reuse plant nutrients from human excreta to agricultural land. Partly because it increases the sustainability of society as the world's supply of many nutrients are finite, partly because it promotes human health, both by reducing disease transmission and by increasing Agricultural production. An untapped resource such as sewage sludge that is rich in nutrients and humus-forming materials could replace parts of the commercial fertilizers used in Sweden today. owever, sewage sludge contains undesirable substances such as heavy metals and drug residues, and Pathogenic microorganisms.

Health is a complex concept and therefore difficult to define. The concept today playsan important role in society as well as in school, due to the inactivity of today?s youth. Thelatest curriculum for the compulsory school, Lpo 94, has increased the focus on the concept ofhealth, as a part of the physical education, but how the teacher chooses to construct theeducation is still up to each individual, which leads to a vast room for personal interpretation.This is the starting-point of our qualitative, ethnographical, study, that has resulted inthis composition. By passively participating during four lessons as well as interviewing twoteachers in physical education we have been able to analyse how the education regarding theconcept of health was constructed.

Pathogenic microorganisms pose a big threat towards food production. Meanwhile, negative impacts on humans and environment are seen by the use of pesticides. Biological control agents are an alternative to the use of chemical pesticides, and plant-growth promoting rhizobacteria, such as Bacillus amyloliquefaciens has been shown to have good properties as biocontrol agents. Before these bacteria can be used commercially their impact on other soil organisms has to be evaluated. This thesis looks into what biocontrol bacteria are and how they might affect earthworms.

Oilseed rape is an important crop in Sweden and is grown on about 90000 ha today. The interest in oil seed pro-duction is increasing because of growing demand and high prices for oil seed both in Sweden and Europe. However, an increased intensity in the oil seed production can bring higher risk of yield losses due to fungal diseases. The purpose of this study was to investigate what different fungi are associated with oilseed rape under field conditions and if their incidence is correlated to crop establishment problems. This study was carried out in three parts: 1) investigations on fungal community structure in roots and rhizosphere soils from young spring- and winter rape plants sampled in failed respectively good establishment patches in four fields, 2) investigations on the pathogenicity of fungi isolated from oilseed rape in controlled environment and 3) investigations on the effect of different fungicide seed treatments on germination and early plant development in a field soil naturally infested with damping off- and Verticillium wilt pathogens. The studies on community structure using a combined approach of standard fungal isolation techniques and DNA based methods revealed a high fungal diversity in three out of four studied fields of spring rape and winter rape. For some unknown reason, very few fungal species were identified from the fourth field.

Globally, coastal ecosystems like mangrove forests, sea grass meadows and salt marshes are well known for their ability to capture and store atmospheric carbon effectively. In Sweden, there is still limited knowledge about local coastal ecosystems with similar functions, with alder swamp forests being an interesting example. Therefore, this study aimed to increase knowledge of the factors that can contribute to the potential carbon sequestering ability of alder swamps. Vegetation data and sediment samples were collected from a total of 37 sampling plots across four alder swamps in Bohusl?n on the Swedish west coast.

One of the main objectives of all food production is to produce foods that can safely beconsumed without fear of being sick. Despite this hundreds of people are affected in Sweden offood poisoning almost every day. Most cases are caused by a small group of so-called pathogenicmicroorganisms. The most frequently affected are the small children, the elderly, persons withreduced resistance and pregnant. The reasons behind the food poisoning are often ignorance andlack of food hygiene.

During the summer 2007 was a scrubber tested at Gruvön papper mill in Grums. The scrubber reduced NOx with 90 % in flue gas. NOx was transferred from the flue gas to a scrubber liquid as nitrate and nitrite. The scrubber liquid needs to be purified from nitrate and nitrite. One possible solution is to clean the scrubber liquid in Gruvön biologic cleaning construction.Microorganisms in the biologic cleaning construction need to assimilate nitrogen. There are environments free from oxygen in the cleaning construction.